Use of Phenylephrine for Assessment of Mitral Regurgitation Severity
Status:
Recruiting
Trial end date:
2021-12-01
Target enrollment:
Participant gender:
Summary
The study proposes to develop a phenylephrine protocol to be used during transesophageal
echocardiography, whereby intravenous phenylephrine would be used to increase afterload with
the intent to mimic the awake hemodynamic profile and variation that occurs with normal
physical activity. The expectation is to see changes in severity of Mitral Regurgitation (MR)
grade with increasing afterload, which in turn can provide more accurate quantification of MR
severity to assist in clinical decision making.