Use of Minocicline in Patients With Stroke

• Status: Unknown status
• Trial end date: 2013-01-01
• Target enrollment: 0
• Participant gender: All

Summary

The investigators will evaluate the National Institute of Health Stroke Scale/Score (NIHSS)in patients with stroke, and then give Minocycline 100mg po every 12 hours or placebo for five days, then perform periodic evaluations to determine the status and degree of neurological sequelae developed.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hospital Universitario Hernando Moncaleano Perdomo

Criteria

Inclusion Criteria:

• NIHSS scale greater than 5

• Onset of symptoms less than 24 hours

• normal Cranial Tomography(CT)

• CT evidence of cerebral ischemia

• Acceptance of study entry

Exclusion Criteria:

• Hemorrhagic cerebrovascular disease

• Other neurological diseases

• Concomitant structural damage

• History of neurosurgery

• Known allergy to tetracyclines

• Concomitant infectious diseases requiring antibiotic treatment.

• History of Stroke

• Women pregnant or breast-feeding