Use of Metformin in Treatment of Childhood Obesity

• Status: Completed
• Trial end date: 2016-04-01
• Target enrollment: 0
• Participant gender: All

Summary

This study expects to evaluate the use of metformin in the management of obese children. Insulin resistance among obese Sri Lankan children (south Asian origin) is high, which had been shown in the investigators previous work.

This study will look at the effect of metformin on changes in insulin resistance, fatty liver state, body fat content, BMI and other metabolic derangement.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Colombo
• Treatments: Metformin

Criteria

Inclusion Criteria:

• Obese children (based on >+2SD of BMI to age on WHO 2007 standards)

Exclusion Criteria:

• Children not of Sri Lankan origin

• Children who are not planning to live in Sri Lanka during the next one year

• Children with a secondary underlying cause for the overweight/obesity