Use of Kudzu Extract in the Study of Its Ability to Reduce Alcohol Drinking in Treatment Seeking Alcohol Dependent Persons

• Status: Withdrawn
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

This research is designed to assess if problem drinking by treatment seeking individuals can be treated (reduced) by kudzu extract pharmacotherapy plus medical management therapy.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Mclean Hospital
• Treatments: Ethanol

Criteria

Inclusion Criteria:

• Treatment seeking for alcohol abuse or dependence.

• Non cigarette smokers are preferred, but will accept those who smoke less than 10 cigarettes per day.

• Marijuana use of less than once per week. Other drug use less than 20 lifetime uses.

• Absence of current Axis I disorders except alcohol abuse or dependence. Past diagnosis (greater than 1 year) is acceptable.

• BMI within 18-30.

• Physically healthy (normal physical exam, ECG, blood and urine chemistries).

• Female participants must use medically approved method of contraception. If barrier method is used, must agree to using two methods simultaneously (e.g., diaphragm and condom).

Exclusion Criteria:

• Taking any prescription medication (except oral contraceptives, certain short term anti -fungal agents and some topical creams for dermal conditions).

• On psychotropic medications.

• Drug use (other than nicotine, alcohol or marijuana) greater than 20 lifetime uses.

• Meets criteria for current drug abuse or dependence (other than alcohol and nicotine). Past abuse/dependence (greater than 3 years) is acceptable.

• History of major head trauma.

• History of cardiac problems.

• Pregnancy, lactating, or planning to become pregnant during the study period.