Use of Cyclosporin A for the Treatment of Recurrent Miscarriage
Status:
Unknown status
Trial end date:
2018-12-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine whether Cyclosporin A (CsA) - an immunosuppressant
drug - in early pregnancy will reduce the risk of miscarriage in women who had a history of
unexplained recurrent miscarriages, as compared with that treated with Dydrogesterone-an
active comparator. The hypothesis is based on the evidence found in vitro and in vivo
experiments that CsA can induce maternal-fetal tolerance so that it may reduce the risk of
miscarriage.