Use of CBD Oil in the Treatment of Posttraumatic Stress Disorder
Status:
Recruiting
Trial end date:
2024-05-01
Target enrollment:
Participant gender:
Summary
The overarching objective of the proposed project is to test the clinical efficacy of CBD in
the treatment of post-traumatic stress disorder using a rigorous double-blind randomized
clinical trial methodology. Participants (n=150) meeting full DSM-5 criteria for
post-traumatic stress disorder (PTSD) will be randomized to one of 3 treatment arms: (a) CBD
-Isolate; (b) CBD-Broad Spectrum; (c) Placebo oil.
We predict that patients receiving CBD isolate or CBD Broad Spectrum will show significantly
greater improvements in PTSD symptoms and functional impairment at the posttreatment, one
month, and three month follow-up assessments relative to patients receiving placebo oil.
Additionally, we expect that patients receiving CBD Broad Spectrum will show significantly
greater improvements relative to patients receiving CBD Isolate.