There are no previous reports on the use of Onabotulinum Toxin A to treat men with scrotal
pain that we found published. We propose a pilot study to use Botox to block the testicular
nerves on a group of 15 men with chronic scrotal pain who have failed the standard medical
therapy. The men must have had temporary relief from a testicular cord block using marcaine.
Before and 1 month, 3 months and 6 months after the Onabotulinum Toxin A injection, the men
would be asked to fill in visual analog scales for pain, a quality of life assessment, a
depression index (MDI) and Chronic Epididymitis Symptom Index (CESI). They will also be
subject to sensory testing of the scrotum before, after 1 month, 3 moths and 6 months.
Phase:
Phase 1
Details
Lead Sponsor:
Mount Sinai Hospital, Canada
Treatments:
abobotulinumtoxinA Botulinum Toxins, Type A incobotulinumtoxinA onabotulinumtoxinA