Use of Biperiden for the Prevention of Post-traumatic Epilepsy
Status:
Recruiting
Trial end date:
2021-07-31
Target enrollment:
Participant gender:
Summary
There is no AED or medication that has been demonstrated to affect the development of
post-traumatic epilepsy. Biperiden is a cholinergic antagonist, acting in the muscarinic
receptor, that is widely used as an anti Parkinson drug. The investigators data with animal
models of epilepsy indicate that anti-muscarinic agents might affect the natural course of
the disease in the case of post-traumatic epilepsy.
Phase:
Phase 3
Details
Lead Sponsor:
Federal University of São Paulo
Collaborators:
Cristália Produtos Químicos Farmacêuticos Ltda. University of Sao Paulo