Use of Autologous Serum Eye-drops as Tears in Patients With Recalcitrant Dry Eye

• Status: Completed
• Trial end date: 2011-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to examine the efficacy and safety of autologous serum eye drops in people with recalcitrant dry eye.

• Phase: Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Singapore National Eye Centre
• Treatments: Ophthalmic Solutions; Tetrahydrozoline

Criteria

Inclusion Criteria:

• Seen at the dry eye service at the Singapore National Eye Centre

• Age between 21 and 75 years old

• Symptomatic for dry eye or VA worse than 6/12 in Snellen chart

• Presence of corneal punctate staining involving central zone

• Exhausted what is considered as standard therapy or therapy that is acceptable to the patient and the physician

• No contraindication for blood extraction/plasmapheresis

Exclusion Criteria:

• HIV/HCV/HBV/syphilis