Overview

Use of Angiotensin-(1-7) in COVID-19

Status:
Completed
Trial end date:
2021-11-01
Target enrollment:
Participant gender:
Summary
The renin-angiotensin system (RAS) has a relevant role in COVID-19, as the virus will enter host's cells via the angiotensin-converting enzyme 2 (ACE2); RAS disequilibrium might also play a key role in the modulation of the inflammatory response that characterizes the lung involvement. Angiotensin-(1-7) is a peptide that could be altered in COVID-19 patient and its supplementation may potentially helpful in this setting.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Erasme University Hospital
Collaborators:
Angitec
Federal University of Minas Gerais
Fonds Erasme pour la Recherche Medicale
Treatments:
Angiotensin I (1-7)