Use of Analgesic Treatment to Reduce Signs of Pain in Patients With Disorders of Consciousness.
Status:
Completed
Trial end date:
2021-04-28
Target enrollment:
Participant gender:
Summary
The purpose of this study is to characterize and improve pain and nociception management in
patients with disorders of consciousness (DOC). This project is divided into two phases, a
first phase to evaluate pain level and a second phase which consist of a clinical trial to
evalute pain medication efficacy.
The main aim is to evaluate the use of the Nociception Coma Scale-Revised (NCS-R) and its
cut-off score (i.e., 5) as an assessment and management tool to define guidelines for
managing pain in patients with DOC. In this double-blind, placebo-controlled clinical study,
we will evaluate the use of analgesic treatments in reducing pain in subacute/chronic
patients. The project will also allow us to validate the NCS-R cut-off score defined
previously.