Ursodeoxycholic Acid for Rhegmatogenous Retinal Detachment
Status:
Completed
Trial end date:
2017-09-01
Target enrollment:
Participant gender:
Summary
26 patients presenting a rhegmatogenous retinal detachment with more than 4 days of duration
will be prospectively included.
A single dose of ursodeoxycholic acid will be administered orally before surgery at different
time-points in 22 subjects. Standard surgery will be performed and ocular samples will be
collected during the procedure. Ursodeoxycholic acid treatment will be continued in treated
patients during 3 months after surgery.
Ocular and serum samples from the 4 untreated patients will serve as negative controls for
the determination of UDCA levels.