Overview

Understanding Rebound Pain After Regional Anesthesia Resolution in Healthy Volunteers

Status:
Completed
Trial end date:
2024-05-28
Target enrollment:
Participant gender:
Summary
Regional anesthesia decreases postoperative pain scores and opioid consumption, and may prevent chronic pain after surgery in patients undergoing surgery. However, some patients experience an increase of pain into the severe range when the nerve block wears off, also known as rebound pain. The investigators are studying if a nerve block (numbing injection) in the arm causes hyperalgesia (increased pain) when the nerve block is wearing off.
Phase:
Phase 1
Details
Lead Sponsor:
Brigham and Women's Hospital
Treatments:
Mepivacaine
Prilocaine