Uncomplicated Skin and Soft Tissue Infections Caused by Community-Associated Methicillin-Resistant Staphylococcus Aureus
Status:
Completed
Trial end date:
2015-02-01
Target enrollment:
Participant gender:
Summary
The purpose of this clinical trial is to evaluate 2 different antibiotics, drugs that fight
bacteria, [clindamycin (CLINDA) and trimethoprim-sulfamethoxazole (TMP-SMX)] and wound care
for the outpatient management of uncomplicated skin and soft tissue infections (uSSTIs) in
children and adults. The study will occur in areas where community associated
methicillin-resistant Staphylococcus (S.) aureus are common. S. aureus is a type of bacteria.
A total of 1310 volunteers, greater than or equal to 6 months of age and adults 85 years or
younger, non-immunocompromised, with uSSTIs (in particular abscess and/or cellulitis) will be
enrolled in this study. Subjects will be treated with one of the following: CLINDA, TMP-SMX,
or placebo (contains no medication). Volunteers will be grouped based on the presence of
cellulitis or abscess, whether the abscess can be surgically drained, and its size. The
subject participation duration for this study is about 6 weeks.
Phase:
Phase 2
Details
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)