Ultra Low Doses of Therapy With Radiation Applicated to COVID-19
Status:
Recruiting
Trial end date:
2021-04-21
Target enrollment:
Participant gender:
Summary
The host response against the coronavirus 2 (SARS-CoV-2) appears to be mediated by a
'cytoquine storm' developing a systemic inflammatory mechanism and an acute respiratory
distress syndrome (ARDS), in the form of a bilateral pneumonitis, requiring invasive
mechanical ventilation (IMV) in an important group of patients.
In terms of preventing progression to the critical phase with the consequent need of
admission to the intensive care units (ICU), it has been recently proposed that this
inflammatory cytoquine-mediated process can be safely treated by a single course of ultra-low
radiotherapy (RT) dose < 1 Gy.
The main purpose of the study was to analyze the efficacy of ultra low-dose pulmonary RT, as
an anti-inflammatory intention in patients with SARS-Cov-2 pneumonia with a poor or no
response to standard medical treatment and without IMV.
Phase:
N/A
Details
Lead Sponsor:
Fundacion GenesisCare
Collaborators:
Hospital La Milagrosa Hospital Vithas Valencia Consuelo