Two-channel IV-PCA With Dexmedetomidine

• Status: Not yet recruiting
• Trial end date: 2023-12-31
• Target enrollment: 0
• Participant gender: All

Summary

Dexmedetomidine was administered in the 'selector' channel and fentanyl in the 'basic & bolus' channel of dual channel intravenous patient-controlled analgesia (IV-PCA) and the amount of opioid consumption was compared. In addition, intensity of pain, postoperative nausea/vomiting, and postoperative delirium was evaluated.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Korea University Guro Hospital
• Treatments: Dexmedetomidine

Criteria

Inclusion Criteria:

• Patients who was scheduled for laparoscopic major abdominal surgery (Gastrectomy, Hepatectomy, Colectomy, Pancreatectomy) under general anesthesia

• Aged ≥ 20 years old

Exclusion Criteria:

• Body mass index ≥35 kg/m2

• American Sociuety of Anesthesiologists physical status > 3

• Severe cardiovascular disorder

• Severe liver or renal dysfunction

• Preoperative dyspnea

• Contraindication to dexmedetomidine (preoperative severe bradycardia (Heart rate <50), atrioventricular block, allergy to dexmedetomidine)

• Preoperative use of opioid, anticonvulsant, antidepressant