Two Strategies of RDS Treatment in Newborns With Birth Weight > 1500 Grams

• Status: Unknown status
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to compare two different treatment strategies for RDS in preterm infants > 1500 grams and evaluate whether a selective surfactant administration would reduce the need of intubation, mechanical ventilation and surfactant use.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Pontificia Universidad Catolica de Chile
• Collaborator: Sociedad Chilena de Pediatría
• Treatments: Pulmonary Surfactants

Criteria

Inclusion Criteria:

• Birth Weight > 1500 g.

• First day of life.

• Clinical and radiological signs of RDS.

• Oxygen requirement over 30% to reach an oxygen saturation of 88%.

• Parent's consent approved.

Exclusion Criteria:

• Neonatal asphyxia, 5 minute Apgar < 3 or cord pH <7.0.

• Cardiac or respiratory malformation.

• Chromosomal disease.

• Significative pneumothorax.