Tumor Hypoxia and Proliferation in Patients With High-Grade Glioma
Status:
Recruiting
Trial end date:
2023-06-30
Target enrollment:
Participant gender:
Summary
This is a pilot study to assess a new methodology developed for High Grade Glioma (HGG).
FMISO PET (Fluoromisonidazole-PET) allows researchers to study whether tumor cells lack
oxygen (hypoxia). FLT PET (Fluorodeoxythymidine-PET) allows researchers to study the increase
in the number of cells as a result of cell growth and cell division (proliferation). Tumors
that have low oxygen levels and/or are dividing fast shall resist to standard cancer
treatment. The study will compare FMISO PET and FLT PET imaging techniques with molecular
biomarkers of hypoxia, angiogenesis, and cellular proliferation in tissue.
proliferation).This information could help researchers develop new treatment techniques to
better treat cancer.