Overview

Triple Versus Quadruple Therapy for the Eradication of Helicobacter Pylori

Status:
ENROLLING_BY_INVITATION
Trial end date:
2025-11-30
Target enrollment:
Participant gender:
Summary
The study aimed to compare the efficacy and safety of 7-day and 14-day vonoprazan-amoxicillin-tetracycline triple therapy with 14-day vonoprazan-amoxicillin-tetracycline-bismuth quadruple therapy for the eradication of Helicobacter pylori. Subjects were randomized to receive the intervention and were reviewed by 13C-urea breath test after 6 weeks. The eradication rates, adverse reaction rates and patient adherence were calculated.
Phase:
NA
Details
Lead Sponsor:
Shandong University
Collaborators:
Binzhou Maternal and Child Health Hospital
Feicheng Municipal People's Hospital
Linyi Yizhou Hospital
Zaozhuang Municipal Hospital
Zibo Maternal and Child Health Hospital
Treatments:
1-(5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine
Amoxicillin
Bismuth
Tetracycline