Tricyclic Antidepressants (TCAs) on Gastric Emptying
Status:
Terminated
Trial end date:
2014-06-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine the effects of two tricyclic antidepressant agents
(TCAs), amitriptyline and desipramine, on gastric emptying and gastric accommodation using a
newly developed scintigraphic test that simultaneously measures both gastric emptying and
gastric volume (accommodation). These two tricyclic antidepressant agents are commonly used
at low doses to treat patients with refractory functional dyspepsia.