Overview

Triclosan Toothpaste in the Maintenance Phase of Peri-implantitis Treatment.

Status:
Completed
Trial end date:
2017-06-01
Target enrollment:
0
Participant gender:
All
Summary
The aim of this study was to evaluate the effects of a dentifrice containing 0.3% triclosan on periodontal and peri-implant parameters in patients, with or without periodontitis, treated for peri-implantitis and that were enrolled in a maintenance phase for two years.
Phase:
Phase 3
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
University of Guarulhos
Collaborator:
Universidade Estadual de Maringá
Treatments:
Anti-Infective Agents
Fluorides
Sodium Fluoride
Triclosan
Criteria
Inclusion Criteria:

- aged between 18-70 years;

- general good health;

- minimum of 1 dental implant in function for at least one year with untreated
peri-implantitis defined as: probing depth (PD) ≥ 5 mm, bleeding on probing (BOP) or
suppuration, radiographic bone loss involving 2 mm from the upper border of the
intrabony portion of the implant.

Exclusion Criteria:

- untreated periodontitis (defined as ≥ 6 sites with PD ≥ 5 mm);

- periodontal treatment within three months prior to entering the study;

- inability to perform proper supragingival plaque control (e.g. due to improper
prosthesis design or lack of skills);

- diabetes;

- pregnancy;

- nursing;

- history of allergies to triclosan, fluoride or any other ingredient of oral care
products;

- alcohol or drug abuse;

- any systemic diseases that could affect post-operative healing;

- any systemic diseases that required antibiotic premedication for routine dental
therapy;

- long-term use of mouthrinses, anti-inflammatory medications or any other drug that
could interfere with the study outcomes within three months prior to entering the
study;

- antibiotics use within six months prior to entering the study;

- participation in any other clinical study within three months prior to entering the
study.