Trial to Understand Efficacy of Colesevelam in Diarrhea Predominant IBS Patients With Bile Acid Malabsorption
Status:
Completed
Trial end date:
2019-05-31
Target enrollment:
Participant gender:
Summary
To compare with a randomized trial (n=15 per treatment group), effects of colesevelam and
placebo treatment, on colonic transit, bowel functions, permeability and tight junction
expression in rectosigmoid mucosa of IBS-D with Bile Acid Malabsorption.
Phase:
Phase 2
Details
Lead Sponsor:
Mayo Clinic
Collaborator:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)