Trial on Metoclopramide and Ketoprofen in Acute Migraine of Childhood

• Status: Withdrawn
• Trial end date: 2010-06-01
• Target enrollment: 0
• Participant gender: All

Summary

This is a Randomized double blind trial with the aim to estimate the effectiveness of 3 therapeutic regimes per os on migraine pain:

• metoclopramide 0,15 mg/kg + placebo

• metoclopramide 0,15 mg/Kg + ketoprofen 1 mg/kg

• ketoprofen 1 mg/Kg + placebo

Intensity of pain will be measured with linear 1-10 scale or analogic McGrath type scale every 20 min.

The main objective is the evaluation of healing times from pain in the 3 groups

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: IRCCS Burlo Garofolo
• Treatments: Ketoprofen; Metoclopramide

Criteria

Inclusion Criteria:

• Children 6-17 years old with migraine presenting in emergency room

Exclusion Criteria:

• Informed consensus not obtained

• Occurring migraine still treated

• Hemiplegic migraine