Trial of Zolpidem for Sleep in Children With Autism
Status:
Not yet recruiting
Trial end date:
2027-06-30
Target enrollment:
Participant gender:
Summary
The purpose of this study is to examine the effect of zolpidem on sleep in children and
adolescents with Autism Spectrum Disorder (ASD). Zolpidem is a nonbenzodiazepine GABAa
receptor agonist drug that acts as a hypnotic. To accomplish this, the investigators will use
a randomized double-blind placebo-controlled crossover 8-week study design to examine the
effect of zolpidem on sleep physiology as assessed by polysomnography (PSG), actigraphy,
circadian rhythm, and clinical measures.