Trial of Viagra' in Men With Chronic Pelvic Pain Syndrome Type III
Status:
Terminated
Trial end date:
2007-07-01
Target enrollment:
Participant gender:
Summary
Viagra is a potent 5-PDE inhibitor that causes vasodilation in the penis and, therefore,
erection in men with erectile dysfunction. Our hypothesis is that Viagra may improve the
symptoms of men with Chronic Pelvic Pain Syndrome based on the following assumptions:
Chronic Pelvic Pelvic Syndrome and Interstitial Cystitis involve poorly understood central
and peripheral pain sensitization such as are seen in Chronic Sympathetic Dystrophy, also
called Chronic Regional Pain Syndrome. This pain may be caused by constricted blood vessels
resulting from past stress, injury or trauma
Viagra will dilate sympathetically constricted vessels and improve pelvic blood flow in the
same manner it does in men with erectile dysfunction.
Since men with Chronic Pelvic Pain Syndrome often complain of sexual dysfunction; improving
sexual function and, therefore, quality of life may improve overall well being and perception
of pain.