Overview

Trial of Ultrahypofractionated Focal Salvage Radiotherapy for Isolated Prostate Bed Recurrence After Radical Prostatectomy

Status:
Not yet recruiting

Trial end date:
2027-08-31

Target enrollment:

Participant gender:

Summary

The main objective of the trial is to explore the efficacy and safety of combining short-term androgen deprivation therapy (ADT) over 6 months to focal ultrahypofractionated salvage radiotherapy (SRT) delivered in 5 fractions to the site of local recurrence within the prostate bed after radical prostatectomy where multiparametric magnetic resonance imaging (mpMRI) and prostate-specific membrane antigen (PSMA) PET/CT are used to precisely identify the local recurrence and compare it to previously published literature.

Phase:

N/A

Details

Lead Sponsor:

University Hospital Inselspital, Berne

Collaborators:

Debiopharm International SA
University of Bern
Werner und Hedy Berger-Janser - Stiftung

Treatments:

Androgens