There are currently no treatments to specifically target asthma in obese adults. This pilot
study is being conducted to investigate how effective roflumilast is in treating asthma in
participants that have a higher BMI. Roflumilast can induce weight loss, which may lead to
improved asthma control.
The primary objective of TRIM is to perform a pilot placebo-controlled trial of roflumilast
for the treatment of poorly controlled obese asthmatics.
Phase:
Phase 2
Details
Lead Sponsor:
Johns Hopkins University
Collaborators:
American Lung Association National Heart, Lung, and Blood Institute (NHLBI)