Trial of Pregabalin for Post-operative Pain in Women Undergoing Abdominal Hysterectomy
Status:
Completed
Trial end date:
2011-01-01
Target enrollment:
Participant gender:
Summary
We hypothesize that pregabalin will decrease post-operative pain scores and opioid use
following abdominal hysterectomy compared to placebo. This study has been designed to
determine if after an abdominal hysterectomy, the addition of pregabalin to their
peri-operative analgesia regimen will demonstrate superior analgesia compared to placebo in
terms of lower pain scores and reduced usage of opioids. The primary outcome will be
post-operative pain, measured by total opioid consumption.
Do women undergoing an abdominal hysterectomy with general anesthesia and receiving
pregabalin prior to their surgery and 12 hours later have lower opioid consumption in the
first 24 hours after their surgery than those women who received placebo?