Overview

Trial of PCC Versus FFP in Patients Undergoing Heart Surgery

Status:
Completed
Trial end date:
2020-01-29
Target enrollment:
Participant gender:
Summary
The PROPHESY trial is a single centre pilot trial investigating Fresh Frozen Plasma (FFP) or Prothrombin Complex Concentrate (PCC) treatment for patients who are bleeding during cardiac surgery, and who are NOT receiving a vitamin K antagonist agent (e.g. warfarin). This pilot study will investigate the feasibility of delivering the different components of the trial, so that investigators can determine if it's feasible to move to a future large trial that will aim to compare the efficacy and safety of FFP versus PCC in adult patients who are actively bleeding during cardiac surgery.
Phase:
Phase 2
Details
Lead Sponsor:
Queen Mary University of London
Collaborator:
British Heart Foundation
Treatments:
Thrombin