Trial of Mitomycin C During Nephroureterectomy for Urothelial Carcinoma
Status:
Active, not recruiting
Trial end date:
2023-11-01
Target enrollment:
Participant gender:
Summary
Results of previous studies suggest that the timing of intravesical mitomycin C
administration may impact bladder tumor recurrence rate following radical nephroureterectomy.
This is the first study of its kind to attempt to identify the importance of timing of
mitomycin C administration relative to bladder tumor recurrence rate following radical
nephroureterectomy.This study will investigate the one year bladder tumor recurrence rate in
patients with urothelial carcinoma of the upper urinary tract following intraoperative
administration of mitomycin C during a nephroureterectomy, as well as the time to bladder
tumor recurrence in this patient population.