Trial of Mesalamine for the Treatment of Active Microscopic Colitis
Status:
Completed
Trial end date:
2007-11-01
Target enrollment:
Participant gender:
Summary
Subjects must be 18 years old and older, have diarrhea and microscopic colitis. Pregnant or
nursing females are excluded. They can't have other untreated diarrheal conditions. Subjects
will receive medication for 8 weeks, followed by sigmoidoscopy with biopsies. The subjects
will be monitored weekly. A pathologist will review pre and post treatment biopsies. Subjects
that show improvement will be followed for 4 weeks post medication.
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
Mayo Clinic
Collaborators:
Edward V. Loftus MD Paul E. Evans MD Thomas C. Smryk MD Willaim Tremaine MD William J. Sandborn MD