Trial of Mannitol Cream for Pain Relief After a Long Run

• Status: Completed
• Trial end date: 2013-07-01
• Target enrollment: 0
• Participant gender: All

Summary

Mannitol cream has been shown clinically to be effective for pain control. To determine if this effect is worth testing on a larger scale, 170 runners will receive a sample of 25% mannitol cream to apply on one leg, and the cream base without the mannitol on the other leg following a 10 km or longer run, and for the following five days. Mannitol and control legs will be chosen at random for each runner. Pain scores before and after cream application will be acquired each day for each leg. Means and standard deviations found will be used to determine the size of a larger study.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of British Columbia
• Treatments: Mannitol; Polystyrene sulfonic acid

Criteria

Inclusion Criteria:

either:

• never ran 10 km or more, or;

• NRS pain level greater than 5/10 in both legs following a 10 km or more run

Exclusion Criteria:

• no major skin allergies

• no allergy to mannitol