Trial of MEK Inhibitor and PI3K/mTOR Inhibitor in Subjects With Locally Advanced or Metastatic Solid Tumors
Status:
Completed
Trial end date:
2015-04-01
Target enrollment:
Participant gender:
Summary
This research trial is testing a combination of two experimental drugs, MSC1936369B
(Mitogen-activated protein extracellular signal-regulated kinase (MEK) Inhibitor) and
SAR245409 (Phosphatidylinositol 3-kinase (Pi3K)/Mammalian Target of Rapamycin (mTOR)
inhibitor), in the treatment of locally advanced or metastatic solid tumors. The primary
purpose of the study is to determine the maximum tolerated dose of the drug combination.