Trial of L-DOPA as a Treatment to Improve Vision in Albinism
Status:
Completed
Trial end date:
2014-12-01
Target enrollment:
Participant gender:
Summary
This project will evaluate the effect of two doses of levodopa (L-DOPA) in a randomized,
placebo-controlled, double-masked clinical trial to see if vision can be improved in
individuals with albinism. The hypothesis is that providing L-DOPA to the retinas of these
individuals may increase melanin pigment production. Increased melanin has previously been
shown to be associated with improved vision.
Phase:
Phase 2
Details
Lead Sponsor:
University of Minnesota University of Minnesota - Clinical and Translational Science Institute