Overview

Trial of Induction Chemotherapy With Carboplatin and Paclitaxel, Followed by Concurrent Chemotherapy/Radiation Therapy With ZD1839 (IRESSA), 5-FU, Hydroxyurea, and Twice-Daily Radiation, Followed by Adjuvant ZD1839 Monotherapy in Patients With Local

Status:
Completed

Trial end date:
2018-08-01

Target enrollment:

Participant gender:

Summary

The purpose of this study is to explore the activity of ZD1839 added to concurrent chemoradiotherapy and as adjuvant monotherapy in patients with locally advanced head and neck cancer. Activity is described in terms of response rate (complete responses only).

Phase:

Phase 2

Details

Lead Sponsor:

University of Chicago

Treatments:

Albumin-Bound Paclitaxel
Carboplatin
Gefitinib
Hydroxyurea
Paclitaxel