Overview

Trial of Individualized Adaptive RT in HPV-related High Risk Oropharynx Cancer

Status:
ACTIVE_NOT_RECRUITING
Trial end date:
2026-07-01
Target enrollment:
Participant gender:
Summary
This study seeks to study the population of HPV-related oropharynx cancer patients that appear to be at highest risk for treatment failure with loco-regional failure and distant metastases including cT4 or cN3. The study team aims to determine if it is feasible to use multi-modality imaging (both DCE MRI and FDG-PET) to optimize the radiation boost in high risk p16+ OPSCC with similar or decreased toxicity compared to historic standard therapy.
Phase:
PHASE2
Details
Lead Sponsor:
University of Michigan Rogel Cancer Center
Treatments:
Carboplatin
Cisplatin
Platinum Compounds
Radiation