Overview

Trial for Vaccine Therapy With Dendritic Cells in Patients With Metastatic Malignant Melanoma

Status:
Terminated
Trial end date:
2012-06-01
Target enrollment:
Participant gender:
Summary
In this trial the investigators want to combine chemotherapy with immunotherapy by giving the patients Temozolomide, before vaccination. The investigators have also included hTERT and survivin mRNA in the vaccine. Finally, the investigators want to introduce ex vivo T cell expansion after lymphodepletion for the patients who show an immune response.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Oslo University Hospital
Steinar Aamdal
Treatments:
Temozolomide
Vaccines