Trial and Cost Effectiveness Evaluation of Intra-arterial Thrombectomy in Acute Ischemic Stroke
Status:
Terminated
Trial end date:
2016-03-01
Target enrollment:
Participant gender:
Summary
THRACE is a controled, multicenter and randomized trial.
The primary objective of this study is to determine whether a combined approach intravenous
thrombolysis (IV) + Mechanical thrombectomy is superior to the reference treatment with IV
thrombolysis alone, in the 3 hours of onset of symptoms in patients with occlusion of
proximal cerebral arteries and with a neurological impairment accident (National Institutes
of Health Stroke Scale [NIHSS] ≥ 10).
The second objective is to determine the cost-effectiveness of this procedure compared to the
standard (IV thrombolysis). The assumption is that the combined approach, by improving the
clinical outcome and speed recovery, allows for lower overall costs to the IV thrombolysis in
3 months and less than or at worst neutral to 1 year.