Overview

Trial Evaluating multimOdal toPical Cream In CompArison to pLacebo (TOPICAL)

Status:
Terminated
Trial end date:
2018-05-30
Target enrollment:
0
Participant gender:
All
Summary
Randomized controlled trial regarding the efficacy of a multimodal topical analgesic, Multiprofen, in comparison to placebo cream treatment on knee pain and function in patients with knee osteoarthritis.
Phase:
Phase 2/Phase 3
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
University of Michigan
Collaborators:
McMaster University
Oakville Trafalgar Memorial Hospital
Criteria
Inclusion Criteria:

The inclusion criteria are:

1. adult men or women ages 50-80 years;

2. Diagnosis of symptomatic osteoarthritis of the knee based on clinical and radiographic
criteria;

3. provision of informed consent.

Exclusion Criteria:

The exclusion criteria are:

1. patients with inflammatory osteoarthritis;

2. open wounds or sores over the knee joint;

3. patients that will likely have problems, in the judgment of the investigators, with
maintaining follow-up;

4. Cases involving litigation.