Overview Trial Evaluating PCSK9 Antibody in Subjects With LDL Receptor Abnormalities Status: Completed Trial end date: 2014-01-31 Target enrollment: Participant gender: Summary A study to determine the safety, tolerability, and efficacy of evolocumab (AMG 145) in patients with homozygous familial hypercholesterolemia (HoFH). Phase: Phase 2/Phase 3 Details Lead Sponsor: AmgenTreatments: Evolocumab