Trial Comparing Morphine to Hydromorphone in Elderly Patients With Severe Pain

• Status: Completed
• Trial end date: 2007-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this research study is to determine which opiate pain medication (morphine or hydromorphone (Dilaudid)) is more effective in the treatment of acute pain in patients presenting to the emergency department.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Montefiore Medical Center
• Treatments: Hydromorphone; Morphine

Criteria

Inclusion Criteria:

1. Age greater than 65 years

2. Pain with onset within 7 days

3. ED attending physician's judgment that patient's pain warrants use of parenteral opioids

4. Normal mental status

Exclusion Criteria:

1. Prior use of methadone

2. Use of other opioids or tramadol within past seven days

3. Prior adverse reaction to morphine or hydromorphone

4. Chronic pain syndrome

5. Alcohol intoxication

6. Systolic Blood Pressure <90 mm Hg

7. Use of monoamine oxidase (MAO) inhibitors in past 30 days

8. Elderly patients with a capnometry reading of greater than 46