Trial Comparing Intrathecal Morphine With Placebo In Patients Undergoing Robotic Cardiac Surgery

• Status: Completed
• Trial end date: 2020-09-01
• Target enrollment: 0
• Participant gender: All

Summary

This is a randomized clinical trial in patients undergoing robotic myocardial revascularization with intraoperative extubation. Patients will be randomized into placebo or intrathecal morphine groups to assess postoperative pain scores and patient satisfaction. Patients will also be assessed for side effects from the intervention.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Chicago
• Treatments: Morphine

Criteria

Inclusion Criteria:

• patient undergoing elective robotic myocardial revascularization without anticipated use of cardiopulmonary bypass and with anticipated intraoperative tracheal extubation.

Exclusion Criteria:

• Emergency surgery

• Preoperative use of inotropes/IABP

• Preoperative use of opoids

• Ejection fraction less than 40%

• Anticipated use of cardiopulmonary bypass

• Previous cardiothoracic surgery

• Anticipated postoperative tracheal intubation

• severe pulmonary disease

• morbid obesity (BMI >35 kg/m2)

• severe hepatic impairment

• severe renal dysfunction (creatinine > 1.5)

• any contraindication to intrathecal injection (patient refusal, difficult patient anatomy, pre-existing coagulopathy, morphine allergy)