Trial Comparing Duration of Analgesia After Popliteal Fossa Sciatiac Nerve Block With Ropivacaine 0.5% When Combined With Placebo, Dexamethasone 4mg or Dexamethasone 8 mg

• Status: Withdrawn
• Trial end date: 2014-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose is to find out if the addition of dexamethasone to ropivacaine 0.5% increases the duration of pain relief provided by popliteal sciatic nerve block performed for foot/ankle surgery. The investigators also want to find out if there is a difference between 4 and 8 mg dose of dexamethasone.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Baylor College of Medicine
• Treatments: BB 1101; Dexamethasone; Dexamethasone 21-phosphate; Dexamethasone acetate; Ropivacaine

Criteria

Inclusion Criteria:

• Ages 18-64

• ASA Physcial Status classification 1-3

• Foot and ankle surgery at Ben Taub General Hospital

Exclusion Criteria:

• diabetes mellitus

• peripheral neuropathy

• coagulopathy

• allergy to study drugs

• systemic glucocorticoid treatment (for 2 weeks or more) within 6 months of surgery

• chronic opioid use at home

• patient inability to properly describe pain to investigators

• pregancy

• prisoners

• patient or surgeon refusal