Overview Tremelimumab + Durvalumab Chemotherapy Naive CRPC Status: Recruiting Trial end date: 0000-00-00 Target enrollment: Participant gender: Summary The goal of this clinical research study is to study the safety and tolerability of durvalumab and tremelimumab when given to participants with metastatic (has spread) castration-resistant prostate cancer. Phase: Phase 2 Details Lead Sponsor: M.D. Anderson Cancer CenterCollaborator: MedImmune LLCTreatments: Antibodies, MonoclonalTremelimumab