Treatments for Depression: Drug Versus Psychotherapy

• Status: Completed
• Trial end date: 2009-06-01
• Target enrollment: 0
• Participant gender: All

Summary

This 4-8 month study, with a 2-year follow up period, will compare sertraline (Zoloft®), venlafaxine (Effexor®), supportive-expressive psychotherapy, and placebo to determine which is more effective in treating major depression.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Pennsylvania
• Collaborator: National Institute of Mental Health (NIMH)
• Treatments: Serotonin Uptake Inhibitors; Sertraline; Venlafaxine Hydrochloride

Criteria

Inclusion criteria:

• Major Depressive Disorder diagnosis

Exclusion criteria:

• Psychotic or bipolar disorder diagnosis

• Substance dependence in the last 6 months