Overview

Treatments for COVID-19: Canadian Arm of the SOLIDARITY Trial

Status:
Recruiting
Trial end date:
2022-05-18
Target enrollment:
Participant gender:
Summary
This study is an adaptive, randomized, open-label, controlled clinical trial, in collaboration with countries around the world through the World Health Organization. Subjects will be randomized to receive either standard-of-care products or the study medication plus supportive care, while being hospitalized for COVID-19. Participants will be randomized to one of the following groups: 1. Remdesivir 200mg IV on day 1, followed by 100 mg IV daily infusion for 9 days plus optimized supportive care, OR 2. Interferon-beta-1a, 22 or 44 micrograms subcutaneously on days 1, 3 and 6, plus optimized supportive care OR 3. Optimized support care, all or until discharge from hospital, whichever occurs first
Phase:
Phase 2
Details
Lead Sponsor:
Sunnybrook Health Sciences Centre
Collaborators:
AbbVie
Apotex Inc.
Treatments:
Interferon beta-1a
Interferon-beta
Interferons
Lopinavir
Remdesivir
Ritonavir