Overview

Treatment of Vitamin D Deficiency With Large Bolus Cholecalciferol

Status:
Terminated
Trial end date:
2021-01-15
Target enrollment:
0
Participant gender:
All
Summary
Comparing two treatment regimens (solitary large dose vs daily smaller dose) in patients diagnosed with vitamin D deficiency.
Phase:
Phase 1
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Parkview Adult Medical Center
Parkview Medical Center
Treatments:
Cholecalciferol
Vitamin D
Criteria
Inclusion Criteria:

- age 18-75yrs old

- serum 25(OH)-vitamin D level <20ng/mL

- patient of Parkview Adult Medicine clinic

- not currently on cholecalciferol >2,000IU daily

- no ergocalciferol administration within last week

Exclusion Criteria:

- history of hypercalcemia or hyperparathyroidism

- history of chronic kidney disease with baseline creatinine >1.1

- history of gastric absorption abnormalities

- history of Paget's disease or osteomalacia

- history of thyrotoxicosis

- known malignancy

- currently pregnant

- taking medications for osteoporosis or seizures

- taking more than 1200mg/day of calcium

- inpatient hospitalization at the initiation of study meds