Overview

Treatment of Radiation-induced Fibrosis in the Upper Aerodigestive Tract Cancer by a Combination of Pentoxifylline-tocopherol and Hyperbaric Oxygen

Status:
Unknown status

Trial end date:
2013-07-01

Target enrollment:

Participant gender:

Summary

The pentoxifylline used with tocopherol achieves a certain effectiveness in the treatment of the fibrosis. Hyperbaric oxygen therapy has been recommended and used in a wide variety of medical conditions including the treatment of delayed radiation injuries (soft tissue and bony radiation necrosis). The hyperbaric oxygen therapy increases the formation of granulation tissue and produces angiogenesis maintained after use.

Phase:

Phase 2

Details

Lead Sponsor:

Hospital Universitario de Canarias

Collaborator:

Instituto Médico Tinerfeño IMETISA

Treatments:

alpha-Tocopherol
Pentoxifylline
Tocopherols
Tocotrienols
Vitamin E