Overview

Treatment of Prednisone Plus Cyclophosphamide in Patients With Advanced-stage IgA Nephropathy

Status:
Unknown status
Trial end date:
2019-12-01
Target enrollment:
0
Participant gender:
All
Summary
Treatment of prednisone plus cyclophosphamide may be superior to treatment of prednisone alone in patients with advanced-stage IgA nephropathy.
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Guangdong General Hospital
Guangdong Provincial People's Hospital
Treatments:
Cyclophosphamide
Prednisone
Criteria
Inclusion Criteria:

- biopsy-proven primary IgA nephropathy;

- 18-70 years old;

- elevated serum Creatinine and less than 3.0mg/dl;

- with a written consent from participants to receive prednisone and/or cyclophosphamide

Exclusion Criteria:

- diabetes;

- contraindications for the treatment of prednisone and/or cyclophosphamide;

- any treatment with steroids or immunosuppressive drugs prior to this study;

- acute deterioration of renal function(including those of glomerular origin)