Overview

Treatment of Optic Neuritis With Erythropoietin: a Randomised, Double-blind, Placebo-controlled Trial

Status:
Completed
Trial end date:
2019-11-26
Target enrollment:
Participant gender:
Summary
This clinical trial aims at preventing visual dysfunction and optic nerve degeneration associated with autoimmune optic neuritis by systemic i.v. administration of 33.000 IU erythropoietin over 3 days. The primary objective is to determine the efficacy of erythropoietin compared to placebo given as add-on to methylprednisolone as assessed by measurements of retinal nerve fibre layer thickness and low contrast visual acuity 6 months after acute optic neuritis.
Phase:
Phase 3
Details
Lead Sponsor:
University Eye Hospital, Freiburg
Collaborator:
German Federal Ministry of Education and Research
Treatments:
Epoetin Alfa